Drug developer Kamada Ltd. (TASE: KMDA) today announced positive results in a preclinical trial of its Alpha-1 Antitrypsin (AAT) protein, the active ingredient in its drug, Glassia, which may promote the company's diabetes activity and help it enter other fields.
The AAT Protein in Kamada's Glassia Drug Shows Promise in a Series of Studies that Demonstrate Prevention of Lung Infection and Successful Organ Transplantation:
In several pre-clinical studies performed in Ben Gurion University, lead by Dr Eli Lewis, the Glassia drug by Kamada shows new therapeutic capabilities including being a potential treatment to bacterial lung infection, serving as a strog anti inflammatory agent in COPD and prevention of transplant rejection.
Furthermore, results of Glassia phase 2 study in Type 1 Diabetes (T1D) are expected to be published during the course of this month.
Completion of recruitment was upon meeting the statistical data collection goals required for the study efficacy measures.
The trial will be completed during Q4 2013.
EMA supports Kamada in an open label extension treatment for patients who have completed their trial participation.
David Tsur, Kamada CEO: Completing patient recruitment is a significant achievement for Kamada, further strengthening its position as a global leader in developing the inhaled Alpha-1 antitrypsin”.
The Deloitte Technology Fast 50, one of Israel's foremost technology award programs.
It annually recognizes and honors the 50 private and publicly-held fastest growing technology companies in Israel, based on percentage revenue growth over a five-year period.
The Fast 50 program honors business growth, technological innovation and Israel entrepreneurial spirit.
The Technology Fast 50 is part of a national and international program run by Deloitte.
The company's AATD-IH drug could become the first inhalable treatment for congenital emphysema.
Kamada is currently evaluating strategic collaborations for conducting the Phase II clinical trial in the US.
The Phase II/III trial of AATD-IH, which is already underway in Europe and its results are expected late 2013, may serve the drug approval application to FDA, together with the data from the Phase II study of this IND Approval .
Israeli biopharma company Kamada (KMDA: TA) has entered into an exclusive agreement with privately-owned Italian drugmaker Chiesi Farmaceutici for the distribution of its breakthrough inhaled alpha-1 antitrypsin for treatment of alpha-1 antitrypsin deficiency (AATD-IH), a genetic disorder.
Second quarter revenue rose 11.8% to $13.8 million, and the drug development company raised its full-year revenue guidance to $72 million.
Kamada and Chiesi enter into a strategic agreement for the distribution of Kamada's inhaled AAT drug for treatment of Alpha-1 antitrypsin deficiency in Europe, Turkey and former CIS countries.
The increase was attributable to the rapid sales growth of Glassia, one of the first proprietary drugs developed in Israel to win FDA approval.